Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conju...
Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Significance Self-administered insulin is the most important therapeutic to provide control over blood glucose levels for patients with type-1 diabetes. However, standard insulin therapy introduces a number of complications and subsequent issues with control of blood glucose levels. Here, we prepared a derivative of insulin with a molecular switch...
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Full title
Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4345600
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4345600
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.1424684112