CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
About this item
Full title
Author / Creator
Khairnar, Vishal , Duhan, Vikas , Maney, Sathish Kumar , Honke, Nadine , Shaabani, Namir , Pandyra, Aleksandra A. , Seifert, Marc , Pozdeev, Vitaly , Xu, Haifeng C. , Sharma, Piyush , Baldin, Fabian , Marquardsen, Florian , Merches, Katja , Lang, Elisabeth , Kirschning, Carsten , Westendorf, Astrid M. , Häussinger, Dieter , Lang, Florian , Dittmer, Ulf , Küppers, Ralf , Recher, Mike , Hardt, Cornelia , Scheffrahn, Inka , Beauchemin, Nicole , Göthert, Joachim R. , Singer, Bernhard B. , Lang, Philipp A. and Lang, Karl S.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
B cells are essential for antiviral immune defence because they produce neutralizing antibodies, present antigen and maintain the lymphoid architecture. Here we show that intrinsic signalling of CEACAM1 is essential for generating efficient B-cell responses. Although CEACAM1 exerts limited influence on the proliferation of B cells, expression of CE...
Alternative Titles
Full title
CEACAM1 induces B-cell survival and is essential for protective antiviral antibody production
Authors, Artists and Contributors
Author / Creator
Duhan, Vikas
Maney, Sathish Kumar
Honke, Nadine
Shaabani, Namir
Pandyra, Aleksandra A.
Seifert, Marc
Pozdeev, Vitaly
Xu, Haifeng C.
Sharma, Piyush
Baldin, Fabian
Marquardsen, Florian
Merches, Katja
Lang, Elisabeth
Kirschning, Carsten
Westendorf, Astrid M.
Häussinger, Dieter
Lang, Florian
Dittmer, Ulf
Küppers, Ralf
Recher, Mike
Hardt, Cornelia
Scheffrahn, Inka
Beauchemin, Nicole
Göthert, Joachim R.
Singer, Bernhard B.
Lang, Philipp A.
Lang, Karl S.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346637
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4346637
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7217
