RASAL2 activates RAC1 to promote triple-negative breast cancer progression
RASAL2 activates RAC1 to promote triple-negative breast cancer progression
About this item
Full title
Author / Creator
Feng, Min , Bao, Yi , Li, Zhimei , Li, Juntao , Gong, Min , Lam, Stella , Wang, Jinhua , Marzese, Diego M , Donovan, Nicholas , Tan, Ern Yu , Hoon, Dave S B and Yu, Qiang
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Patients with triple-negative breast cancer (TNBC) have a high incidence of early relapse and metastasis; however, the molecular basis for recurrence in these individuals remains poorly understood. Here, we demonstrate that RASAL2, which encodes a RAS-GTPase-activating protein (RAS-GAP), is a functional target of anti-invasive microRNA-203 and is o...
Alternative Titles
Full title
RASAL2 activates RAC1 to promote triple-negative breast cancer progression
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4348963
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4348963
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI76711
