Long-range epigenetic regulation is conferred by genetic variation located at thousands of independe...
Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci
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Author / Creator
Lemire, Mathieu , Zaidi, Syed H.E. , Ban, Maria , Ge, Bing , Aïssi, Dylan , Germain, Marine , Kassam, Irfahan , Wang, Mike , Zanke, Brent W. , Gagnon, France , Morange, Pierre-Emmanuel , Trégouët, David-Alexandre , Wells, Philip S. , Sawcer, Stephen , Gallinger, Steven , Pastinen, Tomi and Hudson, Thomas J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The interplay between genetic and epigenetic variation is only partially understood. One form of epigenetic variation is methylation at CpG sites, which can be measured as methylation quantitative trait loci (meQTL). Here we report that in a panel of lymphocytes from 1,748 individuals, methylation levels at 1,919 CpG sites are correlated with at le...
Alternative Titles
Full title
Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351585
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351585
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7326
