Transport domain unlocking sets the uptake rate of an aspartate transporter
Transport domain unlocking sets the uptake rate of an aspartate transporter
About this item
Full title
Author / Creator
Akyuz, Nurunisa , Georgieva, Elka R. , Zhou, Zhou , Stolzenberg, Sebastian , Cuendet, Michel A. , Khelashvili, George , Altman, Roger B. , Terry, Daniel S. , Freed, Jack H. , Weinstein, Harel , Boudker, Olga , Blanchard, Scott C. , Brookhaven National Lab. (BNL), Upton, NY (United States) and Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Oak Ridge Leadership Computing Facility (OLCF)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Glutamate transporters terminate neurotransmission by clearing synaptically released glutamate from the extracellular space, allowing repeated rounds of signalling and preventing glutamate-mediated excitotoxicity. Crystallographic studies of a glutamate transporter homologue from the archaeon
Pyrococcus horikoshii
, Glt
Ph
, showed that...
Alternative Titles
Full title
Transport domain unlocking sets the uptake rate of an aspartate transporter
Authors, Artists and Contributors
Author / Creator
Georgieva, Elka R.
Zhou, Zhou
Stolzenberg, Sebastian
Cuendet, Michel A.
Khelashvili, George
Altman, Roger B.
Terry, Daniel S.
Freed, Jack H.
Weinstein, Harel
Boudker, Olga
Blanchard, Scott C.
Brookhaven National Lab. (BNL), Upton, NY (United States)
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Oak Ridge Leadership Computing Facility (OLCF)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351760
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351760
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14158
