PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The human genome encodes a family of nine protein arginine methyltransferases (PRMT1–9), whose members can catalyse three distinct types of methylation on arginine residues. Here we identify two spliceosome-associated proteins—SAP145 and SAP49—as PRMT9-binding partners, linking PRMT9 to U2 snRNP maturation. We show that SAP145 is methylated by PRMT...
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Full title
PRMT9 is a Type II methyltransferase that methylates the splicing factor SAP145
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351962
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4351962
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7428
