Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
About this item
Full title
Author / Creator
Chen, Yulong , Terajima, Masahiko , Yang, Yanan , Sun, Li , Ahn, Young-Ho , Pankova, Daniela , Puperi, Daniel S , Watanabe, Takeshi , Kim, Min P , Blackmon, Shanda H , Rodriguez, Jaime , Liu, Hui , Behrens, Carmen , Wistuba, Ignacio I , Minelli, Rosalba , Scott, Kenneth L , Sanchez-Adams, Johannah , Guilak, Farshid , Pati, Debananda , Thilaganathan, Nishan , Burns, Alan R , Creighton, Chad J , Martinez, Elisabeth D , Zal, Tomasz , Grande-Allen, K Jane , Yamauchi, Mitsuo and Kurie, Jonathan M
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Epithelial tumor metastasis is preceded by an accumulation of collagen cross-links that heighten stromal stiffness and stimulate the invasive properties of tumor cells. However, the biochemical nature of collagen cross-links in cancer is still unclear. Here, we postulated that epithelial tumorigenesis is accompanied by changes in the biochemical ty...
Alternative Titles
Full title
Lysyl hydroxylase 2 induces a collagen cross-link switch in tumor stroma
Authors, Artists and Contributors
Author / Creator
Terajima, Masahiko
Yang, Yanan
Sun, Li
Ahn, Young-Ho
Pankova, Daniela
Puperi, Daniel S
Watanabe, Takeshi
Kim, Min P
Blackmon, Shanda H
Rodriguez, Jaime
Liu, Hui
Behrens, Carmen
Wistuba, Ignacio I
Minelli, Rosalba
Scott, Kenneth L
Sanchez-Adams, Johannah
Guilak, Farshid
Pati, Debananda
Thilaganathan, Nishan
Burns, Alan R
Creighton, Chad J
Martinez, Elisabeth D
Zal, Tomasz
Grande-Allen, K Jane
Yamauchi, Mitsuo
Kurie, Jonathan M
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362236
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362236
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI74725
