Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling
About this item
Full title
Author / Creator
Quinn, Kylie M , Zak, Daniel E , Costa, Andreia , Yamamoto, Ayako , Kastenmuller, Kathrin , Hill, Brenna J , Lynn, Geoffrey M , Darrah, Patricia A , Lindsay, Ross W B , Wang, Lingshu , Cheng, Cheng , Nicosia, Alfredo , Folgori, Antonella , Colloca, Stefano , Cortese, Riccardo , Gostick, Emma , Price, David A , Gall, Jason G D , Roederer, Mario , Aderem, Alan and Seder, Robert A
Publisher
United States: American Society for Clinical Investigation
Journal title
Language
English
Formats
Publication information
Publisher
United States: American Society for Clinical Investigation
Subjects
More information
Scope and Contents
Contents
Recombinant adenoviral vectors (rAds) are lead vaccine candidates for protection against a variety of pathogens, including Ebola, HIV, tuberculosis, and malaria, due to their ability to potently induce T cell immunity in humans. However, the ability to induce protective cellular immunity varies among rAds. Here, we assessed the mechanisms that cont...
Alternative Titles
Full title
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling
Authors, Artists and Contributors
Author / Creator
Zak, Daniel E
Costa, Andreia
Yamamoto, Ayako
Kastenmuller, Kathrin
Hill, Brenna J
Lynn, Geoffrey M
Darrah, Patricia A
Lindsay, Ross W B
Wang, Lingshu
Cheng, Cheng
Nicosia, Alfredo
Folgori, Antonella
Colloca, Stefano
Cortese, Riccardo
Gostick, Emma
Price, David A
Gall, Jason G D
Roederer, Mario
Aderem, Alan
Seder, Robert A
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362254
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4362254
Other Identifiers
ISSN
0021-9738
E-ISSN
1558-8238
DOI
10.1172/JCI78280
