Piezo2 is the major transducer of mechanical forces for touch sensation in mice
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
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Author / Creator
Ranade, Sanjeev S. , Woo, Seung-Hyun , Dubin, Adrienne E. , Moshourab, Rabih A. , Wetzel, Christiane , Petrus, Matt , Mathur, Jayanti , Bégay, Valérie , Coste, Bertrand , Mainquist, James , Wilson, A. J. , Francisco, Allain G. , Reddy, Kritika , Qiu, Zhaozhu , Wood, John N. , Lewin, Gary R. and Patapoutian, Ardem
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Mice lacking the mechanically activated ion channel Piezo2 in both sensory neurons and Merkel cells are almost totally incapable of light-touch sensation while other somatosensory functions, such as mechanical nociception, remain intact, implying that other mechanically activated ion channels must now be identified to account for painful touch sens...
Alternative Titles
Full title
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4380172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4380172
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13980
