5-Hydroxymethylcytosine is a predominantly stable DNA modification
5-Hydroxymethylcytosine is a predominantly stable DNA modification
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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5-Hydroxymethylcytosine (hmC) is an oxidation product of 5-methylcytosine which is present in the deoxyribonucleic acid (DNA) of most mammalian cells. Reduction of hmC levels in DNA is a hallmark of cancers. Elucidating the dynamics of this oxidation reaction and the lifetime of hmC in DNA is fundamental to understanding hmC function. Using stable...
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5-Hydroxymethylcytosine is a predominantly stable DNA modification
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4382525
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4382525
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ISSN
1755-4330
E-ISSN
1755-4349
DOI
10.1038/nchem.2064
