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The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383821

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

About this item

Full title

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

Publisher

Boston: Springer US

Journal title

Molecular and cellular biochemistry, 2015-05, Vol.403 (1-2), p.51-60

Language

English

Formats

Publication information

Publisher

Boston: Springer US

More information

Scope and Contents

Contents

The oxythiamine (OXY) is antivitamin of thiamine. The finding that OXY increases the cytoplasmic concentration of pyruvate, known to enhance collagen biosynthesis, led us to investigate the mechanism of this antivitamin action on collagen biosynthesis in cultured human skin fibroblasts. Confluent fibroblasts were treated with micromolar concentrati...

Alternative Titles

Full title

The mechanism of oxythiamine-induced collagen biosynthesis in cultured fibroblasts

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383821

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4383821

Other Identifiers

ISSN

0300-8177

E-ISSN

1573-4919

DOI

10.1007/s11010-015-2336-z

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