Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
About this item
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Author / Creator
Nussbaum, Claudia , Bannenberg, Sarah , Keul, Petra , Gräler, Markus H. , Gonçalves-de-Albuquerque, Cassiano F. , Korhonen, Hanna , von Wnuck Lipinski, Karin , Heusch, Gerd , de Castro Faria Neto, Hugo C. , Rohwedder, Ina , Göthert, Joachim R. , Prasad, Vysakh Pushpa , Haufe, Günter , Lange-Sperandio, Baerbel , Offermanns, Stefan , Sperandio, Markus and Levkau, Bodo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Sphingosine-1-phosphate (S1P) participates in inflammation; however, its role in leukocyte rolling is still unclear. Here we use intravital microscopy in inflamed mouse cremaster muscle venules and human endothelial cells to show that S1P contributes to P-selectin-dependent leukocyte rolling through endothelial S1P receptor 3 (S1P
3
) and Gα<...
Alternative Titles
Full title
Sphingosine-1-phosphate receptor 3 promotes leukocyte rolling by mobilizing endothelial P-selectin
Authors, Artists and Contributors
Author / Creator
Bannenberg, Sarah
Keul, Petra
Gräler, Markus H.
Gonçalves-de-Albuquerque, Cassiano F.
Korhonen, Hanna
von Wnuck Lipinski, Karin
Heusch, Gerd
de Castro Faria Neto, Hugo C.
Rohwedder, Ina
Göthert, Joachim R.
Prasad, Vysakh Pushpa
Haufe, Günter
Lange-Sperandio, Baerbel
Offermanns, Stefan
Sperandio, Markus
Levkau, Bodo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4396399
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4396399
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms7416
