Normalization of RNA-seq data using factor analysis of control genes or samples
Normalization of RNA-seq data using factor analysis of control genes or samples
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Publisher
New York: Nature Publishing Group US
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English
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New York: Nature Publishing Group US
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Remove unwanted variation (RUV) is a new statistical method for RNA-seq data normalization that uses control genes or samples to improve differential expression analysis.
Normalization of RNA-sequencing (RNA-seq) data has proven essential to ensure accurate inference of expression levels. Here, we show that usual normalization approaches mostly...
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Normalization of RNA-seq data using factor analysis of control genes or samples
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4404308
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4404308
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ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/nbt.2931