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Normalization of RNA-seq data using factor analysis of control genes or samples

Normalization of RNA-seq data using factor analysis of control genes or samples

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4404308

Normalization of RNA-seq data using factor analysis of control genes or samples

About this item

Full title

Normalization of RNA-seq data using factor analysis of control genes or samples

Publisher

New York: Nature Publishing Group US

Journal title

Nature biotechnology, 2014-09, Vol.32 (9), p.896-902

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Remove unwanted variation (RUV) is a new statistical method for RNA-seq data normalization that uses control genes or samples to improve differential expression analysis.
Normalization of RNA-sequencing (RNA-seq) data has proven essential to ensure accurate inference of expression levels. Here, we show that usual normalization approaches mostly...

Alternative Titles

Full title

Normalization of RNA-seq data using factor analysis of control genes or samples

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4404308

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4404308

Other Identifiers

ISSN

1087-0156

E-ISSN

1546-1696

DOI

10.1038/nbt.2931

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