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Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: r...

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: r...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4407324

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study

About this item

Full title

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study

Publisher

England: BioMed Central Ltd

Journal title

Critical care (London, England), 2015-04, Vol.19 (1), p.164-164, Article 164

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Vital drugs may be degraded or sequestered in extracorporeal membrane oxygenation (ECMO) circuits, with lipophilic drugs considered to be particularly vulnerable. However, the circuit effects on protein-bound drugs have not been fully elucidated. The aim of this experimental study was to investigate the influence of plasma protein binding on drug d...

Alternative Titles

Full title

Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4407324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4407324

Other Identifiers

ISSN

1364-8535

E-ISSN

1466-609X,1364-8535,1366-609X

DOI

10.1186/s13054-015-0891-z

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