Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: r...
Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study
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Publisher
England: BioMed Central Ltd
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English
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Publisher
England: BioMed Central Ltd
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Contents
Vital drugs may be degraded or sequestered in extracorporeal membrane oxygenation (ECMO) circuits, with lipophilic drugs considered to be particularly vulnerable. However, the circuit effects on protein-bound drugs have not been fully elucidated. The aim of this experimental study was to investigate the influence of plasma protein binding on drug d...
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Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4407324
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4407324
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ISSN
1364-8535
E-ISSN
1466-609X,1364-8535,1366-609X
DOI
10.1186/s13054-015-0891-z