Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Purpose:
This study aimed to quantify the probability of overdiagnosis of prostate cancer by polygenic risk.
Methods:
We calculated the polygenic risk score based on 66 known prostate cancer susceptibility variants for 17,012 men aged 50–69 years (9,404 men identified with prostate cancer and 7,608 with no cancer) derived from three UK-bas...
Alternative Titles
Full title
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4430305
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4430305
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/gim.2014.192
