N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate...
N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
About this item
Full title
Author / Creator
Publisher
United States: Elsevier B.V
Journal title
Language
English
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Publisher
United States: Elsevier B.V
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More information
Scope and Contents
Contents
Taxane-based chemotherapy is an effective treatment for castration-resistant-prostate cancer (CRPC) via stabilization of microtubules. Previous studies identified that the inhibitory effect of microtubule-targeting chemotherapy on androgen receptor (AR) activity was conferred by interfering with AR intracellular trafficking. The N-terminal domain (...
Alternative Titles
Full title
N-terminal targeting of androgen receptor variant enhances response of castration resistant prostate cancer to taxane chemotherapy
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4433435
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4433435
Other Identifiers
ISSN
1574-7891
E-ISSN
1878-0261
DOI
10.1016/j.molonc.2014.10.014
