Mutation signatures implicate aristolochic acid in bladder cancer development
Mutation signatures implicate aristolochic acid in bladder cancer development
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Publisher
England: BioMed Central Ltd
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Language
English
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Publisher
England: BioMed Central Ltd
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Contents
Aristolochic acid (AA) is a natural compound found in many plants of the Aristolochia genus, and these plants are widely used in traditional medicines for numerous conditions and for weight loss. Previous work has connected AA-mutagenesis to upper-tract urothelial cell carcinomas and hepatocellular carcinomas. We hypothesize that AA may also contri...
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Full title
Mutation signatures implicate aristolochic acid in bladder cancer development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443665
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4443665
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ISSN
1756-994X
E-ISSN
1756-994X
DOI
10.1186/s13073-015-0161-3
