Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolys...
Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Chaperone-mediated autophagy (CMA) selectively degrades a subset of cytosolic proteins in lysosomes. A potent physiological activator of CMA is nutrient deprivation, a condition in which intracellular triglyceride stores or lipid droplets (LDs) also undergo hydrolysis (lipolysis) to generate free fatty acids for energetic purposes. Here we report t...
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Degradation of lipid droplet-associated proteins by chaperone-mediated autophagy facilitates lipolysis
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4449813
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4449813
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ISSN
1465-7392
E-ISSN
1476-4679
DOI
10.1038/ncb3166
