The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected...
The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected with its iron binding ability
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Author / Creator
Wang, Jun , Bi, Mingxia , Liu, Huiying , Song, Ning and Xie, Junxia
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Lactoferrin (Lf) can bind to lactoferrin receptor (LfR), leading to iron transport through the plasma membrane. Besides iron transportation, Lf also has antioxidant and anti-inflammatory properties. In the brain, Lf is only synthesized by activated microglia. LfR is present in blood vessels and nigral dopaminergic neurons. Both nigral iron accumula...
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Full title
The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected with its iron binding ability
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4451802
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4451802
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep10729