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The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected...

The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4451802

The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected with its iron binding ability

About this item

Full title

The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected with its iron binding ability

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-06, Vol.5 (1), p.10729, Article 10729

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Lactoferrin (Lf) can bind to lactoferrin receptor (LfR), leading to iron transport through the plasma membrane. Besides iron transportation, Lf also has antioxidant and anti-inflammatory properties. In the brain, Lf is only synthesized by activated microglia. LfR is present in blood vessels and nigral dopaminergic neurons. Both nigral iron accumula...

Alternative Titles

Full title

The protective effect of lactoferrin on ventral mesencephalon neurons against MPP+ is not connected with its iron binding ability

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4451802

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4451802

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep10729

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