Structure and insights into the function of a Ca2+-activated Cl− channel
Structure and insights into the function of a Ca2+-activated Cl− channel
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Publisher
London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Contents
Bestrophin calcium-activated chloride channels (CaCCs) regulate the flow of chloride and other monovalent anions across cellular membranes in response to intracellular calcium (Ca
2+
) levels. Mutations in bestrophin 1 (BEST1) cause certain eye diseases. Here we present X-ray structures of chicken BEST1–Fab complexes, at 2.85 Å resolution, wi...
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Full title
Structure and insights into the function of a Ca2+-activated Cl− channel
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4454446
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4454446
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature13913
