New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine...
New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Natural peptides show high degrees of specificity in their biological action. However, their therapeutical profile is severely limited by their conformational freedom and metabolic instability. Stapled peptides constitute a solution to these problems and access to these structures lies on a limited number of reactions involving the use of non-natur...
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Full title
New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4455059
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4455059
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8160