Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Using human bladder cancer xenograft models, a new mechanism involving an active proliferative response of cancer stem cells to chemotherapy-induced damage is shown, driven by prostaglandin E
2
(PGE
2
) release in a manner similar to PGE
2
-induced wound repair; pharmacological inhibition of the PGE
2
/COX2 axis by celecoxib...
Alternative Titles
Full title
Blocking PGE2-induced tumour repopulation abrogates bladder cancer chemoresistance
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4465385
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4465385
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14034
