Dynactin functions as both a dynamic tether and brake during dynein-driven motility
Dynactin functions as both a dynamic tether and brake during dynein-driven motility
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Dynactin is an essential cofactor for most cellular functions of the microtubule motor cytoplasmic dynein, but the mechanism by which dynactin activates dynein remains unclear. Here we use single molecule approaches to investigate dynein regulation by the dynactin subunit p150
Glued
. We investigate the formation and motility of a dynein-p150...
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Full title
Dynactin functions as both a dynamic tether and brake during dynein-driven motility
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4470572
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4470572
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms5807
