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X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4470617

X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

About this item

Full title

X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

Publisher

United States: Massachusetts Medical Society

Journal title

The New England journal of medicine, 2015-05, Vol.372 (22), p.2097-2107

Language

English

Formats

Publication information

Publisher

United States: Massachusetts Medical Society

More information

Scope and Contents

Contents

Some genetic causes of male infertility have been identified, but most remain unknown. In this study, 7 of 289 men with azoospermia (2.4%) harbored a mutation in
TEX11,
a gene expressed in the testes that is critical to chromosomal recombination.
Nearly half of all cases of male infertility are thought to be associated with genetic defects...

Alternative Titles

Full title

X-Linked TEX11 Mutations, Meiotic Arrest, and Azoospermia in Infertile Men

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4470617

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4470617

Other Identifiers

ISSN

0028-4793

E-ISSN

1533-4406

DOI

10.1056/NEJMoa1406192

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