Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
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Author / Creator
Chen, Hongwei , Aksoy, Irène , Gonnot, Fabrice , Osteil, Pierre , Aubry, Maxime , Hamela, Claire , Rognard, Cloé , Hochard, Arnaud , Voisin, Sophie , Fontaine, Emeline , Mure, Magali , Afanassieff, Marielle , Cleroux, Elouan , Guibert, Sylvain , Chen, Jiaxuan , Vallot, Céline , Acloque, Hervé , Genthon, Clémence , Donnadieu, Cécile , De Vos, John , Sanlaville, Damien , Guérin, Jean- François , Weber, Michael , Stanton, Lawrence W , Rougeulle, Claire , Pain, Bertrand , Bourillot, Pierre-Yves and Savatier, Pierre
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Leukemia inhibitory factor (LIF)/STAT3 signalling is a hallmark of naive pluripotency in rodent pluripotent stem cells (PSCs), whereas fibroblast growth factor (FGF)-2 and activin/nodal signalling is required to sustain self-renewal of human PSCs in a condition referred to as the primed state. It is unknown why LIF/STAT3 signalling alone fails to s...
Alternative Titles
Full title
Reinforcement of STAT3 activity reprogrammes human embryonic stem cells to naive-like pluripotency
Authors, Artists and Contributors
Author / Creator
Aksoy, Irène
Gonnot, Fabrice
Osteil, Pierre
Aubry, Maxime
Hamela, Claire
Rognard, Cloé
Hochard, Arnaud
Voisin, Sophie
Fontaine, Emeline
Mure, Magali
Afanassieff, Marielle
Cleroux, Elouan
Guibert, Sylvain
Chen, Jiaxuan
Vallot, Céline
Acloque, Hervé
Genthon, Clémence
Donnadieu, Cécile
De Vos, John
Sanlaville, Damien
Guérin, Jean- François
Weber, Michael
Stanton, Lawrence W
Rougeulle, Claire
Pain, Bertrand
Bourillot, Pierre-Yves
Savatier, Pierre
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4479042
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4479042
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8095
