MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
MAD2L2 regulates DNA repair at deprotected telomeres and at ionizing-radiation-induced double-stranded DNA breaks by inhibiting resection of the 5′ ends; the ends are thus shunted into the non-homologous end-joining pathway.
MAD2L2/REV7 promotes genome integrity
DNA polymerase ζ, composed of REV3, REV7 and an associated factor, REV1, mediates...
Alternative Titles
Full title
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4481296
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14216
