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Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4486416

Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

About this item

Full title

Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2012-12, Vol.338 (6113), p.1476-1480

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

The formation of repetitive structures (such as stripes) in nature is often consistent with a reaction-diffusion mechanism, or Turing model, of self-organizing systems. We used mouse genetics to analyze how digit patterning (an iterative digit/nondigit pattern) is generated. We showed that the progressive reduction in Hoxa13 and Hoxd11-Hoxd13 genes...

Alternative Titles

Full title

Hox Genes Regulate Digit Patterning by Controlling the Wavelength of a Turing-Type Mechanism

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4486416

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4486416

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1226804

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