Insights into the origin of the nuclear localization signals in conserved ribosomal proteins
Insights into the origin of the nuclear localization signals in conserved ribosomal proteins
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Eukaryotic ribosomal proteins, unlike their bacterial homologues, possess nuclear localization signals (NLSs) to enter the cell nucleus during ribosome assembly. Here we provide a comprehensive comparison of bacterial and eukaryotic ribosomes to show that NLSs appear in conserved ribosomal proteins via remodelling of their RNA-binding domains. This...
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Full title
Insights into the origin of the nuclear localization signals in conserved ribosomal proteins
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4490412
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4490412
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms8382