Monocyte:T‐cell interaction regulates human T‐cell activation through a CD28/CD46 crosstalk
Monocyte:T‐cell interaction regulates human T‐cell activation through a CD28/CD46 crosstalk
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Publisher
United States: Nature Publishing Group
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Language
English
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Publisher
United States: Nature Publishing Group
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Contents
T‐cell activation requires engagement of the T‐cell receptor and of at least one costimulatory molecule. The key role of CD28 in inducing T‐cell activation was reported several decades ago and the molecular mechanisms involved have now been well described. The complement regulator CD46 also acts as a costimulatory molecule for T cells but, in contr...
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Full title
Monocyte:T‐cell interaction regulates human T‐cell activation through a CD28/CD46 crosstalk
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4519525
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4519525
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ISSN
0818-9641
E-ISSN
1440-1711
DOI
10.1038/icb.2015.42
