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An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4520751

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

About this item

Full title

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

Publisher

New York: Nature Publishing Group US

Journal title

Nature genetics, 2015-08, Vol.47 (8), p.878-887

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Richard Gilbertson and colleagues report an
in vivo
screen of 84 candidate oncogenes and 39 candidate tumor-suppressor genes in ependymoma mouse models. The validated targets are involved in vesicle trafficking, DNA modification and cholesterol biosynthesis.
Cancers are characterized by non-random chromosome copy number alterations that pr...

Alternative Titles

Full title

An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4520751

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4520751

Other Identifiers

ISSN

1061-4036

E-ISSN

1546-1718

DOI

10.1038/ng.3323

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