An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes
An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes
About this item
Full title
Author / Creator
Mohankumar, Kumarasamypet M , Currle, David S , White, Elsie , Boulos, Nidal , Dapper, Jason , Eden, Christopher , Nimmervoll, Birgit , Thiruvenkatam, Radhika , Connelly, Michele , Kranenburg, Tanya A , Neale, Geoffrey , Olsen, Scott , Wang, Yong-Dong , Finkelstein, David , Wright, Karen , Gupta, Kirti , Ellison, David W , Thomas, Arzu Onar and Gilbertson, Richard J
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Richard Gilbertson and colleagues report an
in vivo
screen of 84 candidate oncogenes and 39 candidate tumor-suppressor genes in ependymoma mouse models. The validated targets are involved in vesicle trafficking, DNA modification and cholesterol biosynthesis.
Cancers are characterized by non-random chromosome copy number alterations that pr...
Alternative Titles
Full title
An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes
Authors, Artists and Contributors
Author / Creator
Currle, David S
White, Elsie
Boulos, Nidal
Dapper, Jason
Eden, Christopher
Nimmervoll, Birgit
Thiruvenkatam, Radhika
Connelly, Michele
Kranenburg, Tanya A
Neale, Geoffrey
Olsen, Scott
Wang, Yong-Dong
Finkelstein, David
Wright, Karen
Gupta, Kirti
Ellison, David W
Thomas, Arzu Onar
Gilbertson, Richard J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4520751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4520751
Other Identifiers
ISSN
1061-4036
E-ISSN
1546-1718
DOI
10.1038/ng.3323
