Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
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Kang, Yanyong , Zhou, X. Edward , Gao, Xiang , He, Yuanzheng , Liu, Wei , Ishchenko, Andrii , Barty, Anton , White, Thomas A. , Yefanov, Oleksandr , Han, Gye Won , Xu, Qingping , de Waal, Parker W. , Ke, Jiyuan , Tan, M. H. Eileen , Zhang, Chenghai , Moeller, Arne , West, Graham M. , Pascal, Bruce D. , Van Eps, Ned , Caro, Lydia N. , Vishnivetskiy, Sergey A. , Lee, Regina J. , Suino-Powell, Kelly M. , Gu, Xin , Pal, Kuntal , Ma, Jinming , Zhi, Xiaoyong , Boutet, Sébastien , Williams, Garth J. , Messerschmidt, Marc , Gati, Cornelius , Zatsepin, Nadia A. , Wang, Dingjie , James, Daniel , Basu, Shibom , Roy-Chowdhury, Shatabdi , Conrad, Chelsie E. , Coe, Jesse , Liu, Haiguang , Lisova, Stella , Kupitz, Christopher , Grotjohann, Ingo , Fromme, Raimund , Jiang, Yi , Tan, Minjia , Yang, Huaiyu , Li, Jun , Wang, Meitian , Zheng, Zhong , Li, Dianfan , Howe, Nicole , Zhao, Yingming , Standfuss, Jörg , Diederichs, Kay , Dong, Yuhui , Potter, Clinton S. , Carragher, Bridget , Caffrey, Martin , Jiang, Hualiang , Chapman, Henry N. , Spence, John C. H. , Fromme, Petra , Weierstall, Uwe , Ernst, Oliver P. , Katritch, Vsevolod , Gurevich, Vsevolod V. , Griffin, Patrick R. , Hubbell, Wayne L. , Stevens, Raymond C. , Cherezov, Vadim , Melcher, Karsten , Xu, H. Eric and Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
G-protein-coupled receptors (GPCRs) signal primarily through G proteins or arrestins. Arrestin binding to GPCRs blocks G protein interaction and redirects signalling to numerous G-protein-independent pathways. Here we report the crystal structure of a constitutively active form of human rhodopsin bound to a pre-activated form of the mouse visual ar...
Alternative Titles
Full title
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Authors, Artists and Contributors
Author / Creator
Zhou, X. Edward
Gao, Xiang
He, Yuanzheng
Liu, Wei
Ishchenko, Andrii
Barty, Anton
White, Thomas A.
Yefanov, Oleksandr
Han, Gye Won
Xu, Qingping
de Waal, Parker W.
Ke, Jiyuan
Tan, M. H. Eileen
Zhang, Chenghai
Moeller, Arne
West, Graham M.
Pascal, Bruce D.
Van Eps, Ned
Caro, Lydia N.
Vishnivetskiy, Sergey A.
Lee, Regina J.
Suino-Powell, Kelly M.
Gu, Xin
Pal, Kuntal
Ma, Jinming
Zhi, Xiaoyong
Boutet, Sébastien
Williams, Garth J.
Messerschmidt, Marc
Gati, Cornelius
Zatsepin, Nadia A.
Wang, Dingjie
James, Daniel
Basu, Shibom
Roy-Chowdhury, Shatabdi
Conrad, Chelsie E.
Coe, Jesse
Liu, Haiguang
Lisova, Stella
Kupitz, Christopher
Grotjohann, Ingo
Fromme, Raimund
Jiang, Yi
Tan, Minjia
Yang, Huaiyu
Li, Jun
Wang, Meitian
Zheng, Zhong
Li, Dianfan
Howe, Nicole
Zhao, Yingming
Standfuss, Jörg
Diederichs, Kay
Dong, Yuhui
Potter, Clinton S.
Carragher, Bridget
Caffrey, Martin
Jiang, Hualiang
Chapman, Henry N.
Spence, John C. H.
Fromme, Petra
Weierstall, Uwe
Ernst, Oliver P.
Katritch, Vsevolod
Gurevich, Vsevolod V.
Griffin, Patrick R.
Hubbell, Wayne L.
Stevens, Raymond C.
Cherezov, Vadim
Melcher, Karsten
Xu, H. Eric
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4521999
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4521999
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14656
