Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
About this item
Full title
Author / Creator
Najm, Fadi J. , Madhavan, Mayur , Zaremba, Anita , Shick, Elizabeth , Karl, Robert T. , Factor, Daniel C. , Miller, Tyler E. , Nevin, Zachary S. , Kantor, Christopher , Sargent, Alex , Quick, Kevin L. , Schlatzer, Daniela M. , Tang, Hong , Papoian, Ruben , Brimacombe, Kyle R. , Shen, Min , Boxer, Matthew B. , Jadhav, Ajit , Robinson, Andrew P. , Podojil, Joseph R. , Miller, Stephen D. , Miller, Robert H. and Tesar, Paul J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Two drugs, miconazole and clobetasol, have functions that modulate differentiation of oligodendrocyte progenitor cells directly, enhance remyelination, and significantly reduce disease severity in mouse models of multiple sclerosis.
Remyelination in multiple sclerosis
Multiple sclerosis is characterized by an autoimmune response and failure o...
Alternative Titles
Full title
Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo
Authors, Artists and Contributors
Author / Creator
Madhavan, Mayur
Zaremba, Anita
Shick, Elizabeth
Karl, Robert T.
Factor, Daniel C.
Miller, Tyler E.
Nevin, Zachary S.
Kantor, Christopher
Sargent, Alex
Quick, Kevin L.
Schlatzer, Daniela M.
Tang, Hong
Papoian, Ruben
Brimacombe, Kyle R.
Shen, Min
Boxer, Matthew B.
Jadhav, Ajit
Robinson, Andrew P.
Podojil, Joseph R.
Miller, Stephen D.
Miller, Robert H.
Tesar, Paul J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528969
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4528969
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14335
