Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds
Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
Although enzymes are able to cleave amide bonds in nature, it is difficult to selectively break the carbon–nitrogen bond of an amide using synthetic chemistry; now the activation and cleavage of these bonds using nickel catalysts is used to convert amides to esters.
Amide C–N bonds activated by nickel catalysis
Although enzymes are able to cl...
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Full title
Conversion of amides to esters by the nickel-catalysed activation of amide C–N bonds
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4529356
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4529356
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature14615
