Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthe...
Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Language
English
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Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
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Filamentous tau inclusions are hallmarks of Alzheimer’s disease (AD) and other neurodegenerative tauopathies. An increasing number of studies implicate the cell-to-cell propagation of tau pathology in the progression of tauopathies. We recently showed (Iba et al., J Neurosci 33:1024–1037,
2013
) that inoculation of preformed synthetic tau fib...
Alternative Titles
Full title
Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4545685
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4545685
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ISSN
0001-6322
E-ISSN
1432-0533
DOI
10.1007/s00401-015-1458-4
