Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs
Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs
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Publisher
United States: Oxford University Press
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Language
English
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Publisher
United States: Oxford University Press
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Scope and Contents
Contents
Ebola virus (EBOV) uses transcriptional editing to express several glycoproteins (GPs), including secreted soluble GP (sGP) and structural GP₁,₂, from a single gene. Recombinant viruses predominantly expressing GP₁,₂ are known to rapidly mutate and acquire an editing site predominantly expressing sGP in vivo, suggesting an important role of this pr...
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Full title
Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564536
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564536
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ISSN
0022-1899
E-ISSN
1537-6613
DOI
10.1093/infdis/jiv111