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Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564536

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

About this item

Full title

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

Publisher

United States: Oxford University Press

Journal title

The Journal of infectious diseases, 2015-10, Vol.212 (suppl 2), p.S242-S246

Language

English

Formats

Publication information

Publisher

United States: Oxford University Press

More information

Scope and Contents

Contents

Ebola virus (EBOV) uses transcriptional editing to express several glycoproteins (GPs), including secreted soluble GP (sGP) and structural GP₁,₂, from a single gene. Recombinant viruses predominantly expressing GP₁,₂ are known to rapidly mutate and acquire an editing site predominantly expressing sGP in vivo, suggesting an important role of this pr...

Alternative Titles

Full title

Soluble Glycoprotein Is Not Required for Ebola Virus Virulence in Guinea Pigs

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564536

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564536

Other Identifiers

ISSN

0022-1899

E-ISSN

1537-6613

DOI

10.1093/infdis/jiv111

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