CtIP tetramer assembly is required for DNA-end resection and repair
CtIP tetramer assembly is required for DNA-end resection and repair
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
CtIP helps maintain genomic stability by promoting DNA double-strand-break repair. Structural and biophysical analyses now show that the N terminus of human CtIP forms a tetrameric structure that is required for resection of broken DNA ends to permit their repair by homologous recombination.
Mammalian CtIP protein has major roles in DNA double-s...
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Full title
CtIP tetramer assembly is required for DNA-end resection and repair
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564947
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4564947
Other Identifiers
ISSN
1545-9993
E-ISSN
1545-9985
DOI
10.1038/nsmb.2937
