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Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4572895

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

About this item

Full title

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Publisher

Durham, NC, USA: AlphaMed Press

Journal title

Stem cells translational medicine, 2015-10, Vol.4 (10), p.1101-1108

Language

English

Formats

Publication information

Publisher

Durham, NC, USA: AlphaMed Press

More information

Scope and Contents

Contents

Primary human fibroblasts were cultured in either insulin‐rich defined medium or in a conventional medium to study the significance of proliferation/growth factor signaling for reprogramming. A direct inverse correlation of high cell proliferation and reprogramming efficiency was seen in human somatic cells grown in the defined medium. These result...

Alternative Titles

Full title

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4572895

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4572895

Other Identifiers

ISSN

2157-6564

E-ISSN

2157-6580

DOI

10.5966/sctm.2014-0217

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