Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts
Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts
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Publisher
Durham, NC, USA: AlphaMed Press
Journal title
Language
English
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Publication information
Publisher
Durham, NC, USA: AlphaMed Press
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Scope and Contents
Contents
Primary human fibroblasts were cultured in either insulin‐rich defined medium or in a conventional medium to study the significance of proliferation/growth factor signaling for reprogramming. A direct inverse correlation of high cell proliferation and reprogramming efficiency was seen in human somatic cells grown in the defined medium. These result...
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Full title
Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts
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Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4572895
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4572895
Other Identifiers
ISSN
2157-6564
E-ISSN
2157-6580
DOI
10.5966/sctm.2014-0217