NSAIDs Ibuprofen, Indometacin and Diclofenac do not interact with Farnesoid X Receptor
NSAIDs Ibuprofen, Indometacin and Diclofenac do not interact with Farnesoid X Receptor
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The nuclear farnesoid X receptor (FXR) is a ligand activated transcription factor and acts as cellular sensor for bile acids. In this role, FXR is a highly important liver protector and FXR inhibition by antagonists or knockout has shown several deleterious effects. A recent report characterized non-steroidal anti-rheumatic drugs (NSAIDs) such as i...
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NSAIDs Ibuprofen, Indometacin and Diclofenac do not interact with Farnesoid X Receptor
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4589779
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4589779
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep14782
