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Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607132

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment

About this item

Full title

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-10, Vol.125 (10), p.3891-3903

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

In many organs, including the intestine and skin, cancers originate from cells of the stem or progenitor compartment. Despite its nomenclature, the cellular origin of hepatocellular carcinoma (HCC) remains elusive. In contrast to most organs, the liver lacks a defined stem cell population for organ maintenance. Previous studies suggest that both he...

Alternative Titles

Full title

Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607132

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4607132

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI77995

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