Pretreatment but not subsequent coincubation with midazolam reduces the cytotoxicity of temozolomide...
Pretreatment but not subsequent coincubation with midazolam reduces the cytotoxicity of temozolomide in neuroblastoma cells
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Publisher
England: BioMed Central Ltd
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Language
English
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England: BioMed Central Ltd
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Temozolomide (TMZ) induces a G2/M cell cycle arrest and is used for treatment of paediatric tumours, especially neuroblastomas. Patients treated with TMZ frequently receive midazolam for sedation prior to surgery and other interventions. Previous studies suggested both cytoprotective and apoptosis-inducing properties of midazolam. Therefore, the im...
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Full title
Pretreatment but not subsequent coincubation with midazolam reduces the cytotoxicity of temozolomide in neuroblastoma cells
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4609078
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4609078
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ISSN
1471-2253
E-ISSN
1471-2253
DOI
10.1186/s12871-015-0135-4
