Role of Tet1 and 5-hydroxymethylcytosine in cocaine action
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action
About this item
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Author / Creator
Feng, Jian , Shao, Ningyi , Szulwach, Keith E , Vialou, Vincent , Huynh, Jimmy , Zhong, Chun , Le, Thuc , Ferguson, Deveroux , Cahill, Michael E , Li, Yujing , Koo, Ja Wook , Ribeiro, Efrain , Labonte, Benoit , Laitman, Benjamin M , Estey, David , Stockman, Victoria , Kennedy, Pamela , Couroussé, Thomas , Mensah, Isaac , Turecki, Gustavo , Faull, Kym F , Ming, Guo-li , Song, Hongjun , Fan, Guoping , Casaccia, Patrizia , Shen, Li , Jin, Peng and Nestler, Eric J
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Expression of TET1 dioxygenase, which catalyzes the conversion of 5-methylcytosine to 5-hydroxymethylcytosine, is downregulated by repeated cocaine administration in mouse nucleus accumbens, where it controls cocaine reward. Genome-wide mapping of 5-hydroxymethylcytosine in this brain region reveals novel modes of epigenetic regulation by cocaine.<...
Alternative Titles
Full title
Role of Tet1 and 5-hydroxymethylcytosine in cocaine action
Authors, Artists and Contributors
Author / Creator
Shao, Ningyi
Szulwach, Keith E
Vialou, Vincent
Huynh, Jimmy
Zhong, Chun
Le, Thuc
Ferguson, Deveroux
Cahill, Michael E
Li, Yujing
Koo, Ja Wook
Ribeiro, Efrain
Labonte, Benoit
Laitman, Benjamin M
Estey, David
Stockman, Victoria
Kennedy, Pamela
Couroussé, Thomas
Mensah, Isaac
Turecki, Gustavo
Faull, Kym F
Ming, Guo-li
Song, Hongjun
Fan, Guoping
Casaccia, Patrizia
Shen, Li
Jin, Peng
Nestler, Eric J
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4617315
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4617315
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.3976