Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme
Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA biosynthetic gene from
Magnaporthe oryzae
by finding two TeA-inducing conditions of a low-producing strain. We demonstrate that TeA is synthesized from isoleucine and ace...
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Full title
Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4640141
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4640141
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms9758