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ArticlesPeer ReviewedFull Text
Discovery and applications of nucleoside antibiotics beyond polyoxin
Author / Creator:Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2019-12, Vol.72 (12), p.855-864
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Chemical biology research in RIKEN NPDepo aimed at agricultural applications
Author / Creator:OSADA, Hiroyuki
Publisher:Japan: The Japan Academy
Journal title:Proceedings of the Japan Academy, Series B, 2025, Vol.101(1), pp.8-31
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Chemical and biological studies of reveromycin A
Author / Creator:Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2016-10, Vol.69 (10), p.723-730
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Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme
Author / Creator:Yun, Choong-Soo ; Motoyama, Takayuki ; Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-10, Vol.6 (1), p.8758-8758, Article 8758
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Proteomics-based target identification of natural products affecting cancer metabolism
Author / Creator:Muroi, Makoto ; Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2021-10, Vol.74 (10), p.639-650
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Biosynthesis and biological function of secondary metabolites of the rice blast fungus Pyricularia oryzae
Author / Creator:Motoyama, Takayuki ; Yun, Choong-Soo ; Osada, Hiroyuki
Publisher:Germany: Oxford University Press
Journal title:Journal of industrial microbiology & biotechnology, 2021-12, Vol.48 (9-10), p.1
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Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway
Author / Creator:Ishihama, Nobuaki ; Choi, Seung-won ; Noutoshi, Yoshiteru ; Saska, Ivana ; Asai, Shuta ; Takizawa, Kaori ; He, Sheng Yang ; Osada, Hiroyuki ; Shirasu, Ken
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7303-13, Article 7303
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Identification of a novel sesquiterpene biosynthetic machinery involved in astellolide biosynthesis
Author / Creator:Shinohara, Yasutomo ; Takahashi, Shunji ; Osada, Hiroyuki ; Koyama, Yasuji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.32865-32865, Article 32865
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Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations
Author / Creator:Kobayashi, Hiroki ; Hatakeyama, Hideyuki ; Nishimura, Haruna ; Yokota, Mutsumi ; Suzuki, Sadafumi ; Tomabechi, Yuri ; Shirouzu, Mikako ; Osada, Hiroyuki ; Mimaki, Masakazu ; Goto, Yu-ichi ; Yoshida, Minoru
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2021-03, Vol.17 (3), p.335-343
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6,9-Dihydroxytetrangulol, a novel angucyclinone antibiotic accumulated in kiqO gene disruptant in the biosynthesis of kinanthraquinone
Author / Creator:Sakai, Katsuyuki ; Takao, Risa ; Koshino, Hiroyuki ; Futamura, Yushi ; Osada, Hiroyuki ; Takahashi, Shunji
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2021-09, Vol.74 (9), p.593-595
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Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival
Author / Creator:Kawamura, Tatsuro ; Kawatani, Makoto ; Muroi, Makoto ; Kondoh, Yasumitsu ; Futamura, Yushi ; Aono, Harumi ; Tanaka, Miho ; Honda, Kaori ; Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-05, Vol.6 (1), p.26521-26521, Article 26521
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Cesium tolerance is enhanced by a chemical which binds to BETA-GLUCOSIDASE 23 in Arabidopsis thaliana
Author / Creator:Moon, Ju Yeon ; Adams, Eri ; Miyazaki, Takae ; Kondoh, Yasumitsu ; Muroi, Makoto ; Watanabe, Nobumoto ; Osada, Hiroyuki ; Shin, Ryoung
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-10, Vol.11 (1), p.21109-11, Article 21109
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ArticlesPeer ReviewedFull Text
Osteoclast‐targeting small molecules for the treatment of neoplastic bone metastases
Author / Creator:Kawatani, Makoto ; Osada, Hiroyuki
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 2009-11, Vol.100 (11), p.1999-2005
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β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593
Author / Creator:Panthee, Suresh ; Kito, Naoko ; Hayashi, Teruo ; Shimizu, Takeshi ; Ishikawa, Jun ; Hamamoto, Hiroshi ; Osada, Hiroyuki ; Takahashi, Shunji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-06, Vol.10 (1), p.10230-10230, Article 10230
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ArticlesPeer ReviewedFull Text
Screening of selected ageing-related proteins that extend chronological life span in yeast Saccharomyces cerevisiae
Author / Creator:Lee, Jee Whu ; Ong, Tee Gee ; Samian, Mohammed Razip ; Teh, Aik-Hong ; Watanabe, Nobumoto ; Osada, Hiroyuki ; Ong, Eugene Boon Beng
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-12, Vol.11 (1), p.24148-24148, Article 24148
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ArticlesPeer ReviewedFull Text
Induction of secondary metabolite production by hygromycin B and identification of the 1233A biosynthetic gene cluster with a self-resistance gene
Author / Creator:Kato, Sho ; Motoyama, Takayuki ; Uramoto, Masakazu ; Nogawa, Toshihiko ; Kamakura, Takashi ; Osada, Hiroyuki
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2020-07, Vol.73 (7), p.475-479
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Reprogramming of flagellin receptor responses with surrogate ligands
Author / Creator:Lee, Du-Hwa ; Lee, Ho-Seok ; Choi, Min-Soo ; Parys, Katarzyna ; Honda, Kaori ; Kondoh, Yasumitsu ; Lee, Jung-Min ; Edelbacher, Natalie ; Heo, Geon ; Enugutti, Balaji ; Osada, Hiroyuki ; Shirasu, Ken ; Belkhadir, Youssef
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.9811-14, Article 9811
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ArticlesPeer ReviewedFull Text
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments
Author / Creator:Simpkins, Scott W. ; Deshpande, Raamesh ; Nelson, Justin ; Li, Sheena C. ; Piotrowski, Jeff S. ; Ward, Henry Neil ; Yashiroda, Yoko ; Osada, Hiroyuki ; Yoshida, Minoru ; Boone, Charles ; Myers, Chad L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2019-02, Vol.14 (2), p.415-440
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Uncovering hidden sesquiterpene biosynthetic pathway through expression boost area-mediated productivity enhancement in basidiomycete
Author / Creator:Asai, Shihori ; Tsunematsu, Yuta ; Masuya, Takahiro ; Otaka, Junnosuke ; Osada, Hiroyuki ; Watanabe, Kenji
Publisher:London: Nature Publishing Group UK
Journal title:Journal of antibiotics, 2020-10, Vol.73 (10), p.721-728
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Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons
Author / Creator:Hara, Tomonori ; Toyoshima, Manabu ; Hisano, Yasuko ; Balan, Shabeesh ; Iwayama, Yoshimi ; Aono, Harumi ; Futamura, Yushi ; Osada, Hiroyuki ; Owada, Yuji ; Yoshikawa, Takeo
Publisher:London: Nature Publishing Group UK
Journal title:Translational psychiatry, 2021-05, Vol.11 (1), p.275-275, Article 275
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Showing 1 to 20 of 145 results

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Discovery and applications of nucleoside antibiotics beyond polyoxin

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Chemical biology research in RIKEN NPDepo aimed at agricultural applications

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Chemical and biological studies of reveromycin A

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Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

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Proteomics-based target identification of natural products affecting cancer metabolism

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Biosynthesis and biological function of secondary metabolites of the rice blast fungus Pyricularia oryzae

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Oxicam-type non-steroidal anti-inflammatory drugs inhibit NPR1-mediated salicylic acid pathway

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Identification of a novel sesquiterpene biosynthetic machinery involved in astellolide biosynthesis

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Chemical reversal of abnormalities in cells carrying mitochondrial DNA mutations

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6,9-Dihydroxytetrangulol, a novel angucyclinone antibiotic accumulated in kiqO gene disruptant in the biosynthesis of kinanthraquinone

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Proteomic profiling of small-molecule inhibitors reveals dispensability of MTH1 for cancer cell survival

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Cesium tolerance is enhanced by a chemical which binds to BETA-GLUCOSIDASE 23 in Arabidopsis thaliana

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Osteoclast‐targeting small molecules for the treatment of neoplastic bone metastases

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β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593

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Screening of selected ageing-related proteins that extend chronological life span in yeast Saccharomyces cerevisiae

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Induction of secondary metabolite production by hygromycin B and identification of the 1233A biosynthetic gene cluster with a self-resistance gene

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Reprogramming of flagellin receptor responses with surrogate ligands

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Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments

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Uncovering hidden sesquiterpene biosynthetic pathway through expression boost area-mediated productivity enhancement in basidiomycete

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Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons

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