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Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4653660

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β

About this item

Full title

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β

Publisher

London: Nature Publishing Group UK

Journal title

Scientific reports, 2015-11, Vol.5 (1), p.16941-16941, Article 16941

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Mesenchymal stem cells (MSCs) are recruited to the tumor microenvironment and influence tumor progression; however, how MSCs induce the invasion of cancer cells is not completely understood. Here, we used a 3D coculture model to determine how MSCs affect the migration of invasive breast cancer cells. Coculture with MSCs increases the elongation, di...

Alternative Titles

Full title

Mesenchymal Stem Cells Induce Directional Migration of Invasive Breast Cancer Cells through TGF-β

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4653660

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4653660

Other Identifiers

ISSN

2045-2322

E-ISSN

2045-2322

DOI

10.1038/srep16941

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