Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation
Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation
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Author / Creator
Huebsch, Nathaniel , Lippens, Evi , Lee, Kangwon , Mehta, Manav , Koshy, Sandeep T. , Darnell, Max C. , Desai, Rajiv M. , Madl, Christopher M. , Xu, Maria , Zhao, Xuanhe , Chaudhuri, Ovijit , Verbeke, Catia , Kim, Woo Seob , Alim, Karen , Mammoto, Akiko , Ingber, Donald E. , Duda, Georg N. and Mooney, David J.
Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
The effectiveness of stem cell therapies has been hampered by cell death and limited control over fate. These problems can be partially circumvented by using macroporous biomaterials that improve the survival of transplanted stem cells and provide molecular cues to direct cell phenotype. Stem cell behaviour can also be controlled
in vitro
by...
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Full title
Matrix elasticity of void-forming hydrogels controls transplanted-stem-cell-mediated bone formation
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4654683
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4654683
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ISSN
1476-1122
E-ISSN
1476-4660
DOI
10.1038/nmat4407