Effect of Mutation Order on Myeloproliferative Neoplasms
Effect of Mutation Order on Myeloproliferative Neoplasms
About this item
Full title
Author / Creator
Ortmann, Christina A , Kent, David G , Nangalia, Jyoti , Silber, Yvonne , Wedge, David C , Grinfeld, Jacob , Baxter, E. Joanna , Massie, Charles E , Papaemmanuil, Elli , Menon, Suraj , Godfrey, Anna L , Dimitropoulou, Danai , Guglielmelli, Paola , Bellosillo, Beatriz , Besses, Carles , Döhner, Konstanze , Harrison, Claire N , Vassiliou, George S , Vannucchi, Alessandro , Campbell, Peter J and Green, Anthony R
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
About 10% of myeloproliferative neoplasms carry mutations in both
TET2
and
JAK2
. Clinical presentation, risk of thrombosis, and rates of tumor progression are affected by which gene mutation is acquired first.
Cancers evolve as a consequence of the stepwise accumulation of somatic lesions, with competition between subclones and sequ...
Alternative Titles
Full title
Effect of Mutation Order on Myeloproliferative Neoplasms
Authors, Artists and Contributors
Author / Creator
Kent, David G
Nangalia, Jyoti
Silber, Yvonne
Wedge, David C
Grinfeld, Jacob
Baxter, E. Joanna
Massie, Charles E
Papaemmanuil, Elli
Menon, Suraj
Godfrey, Anna L
Dimitropoulou, Danai
Guglielmelli, Paola
Bellosillo, Beatriz
Besses, Carles
Döhner, Konstanze
Harrison, Claire N
Vassiliou, George S
Vannucchi, Alessandro
Campbell, Peter J
Green, Anthony R
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4660033
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4660033
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa1412098
