Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation
Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Endogenous neural stem cells in the adult hippocampus are generally considered to be bi-potent. The authors show in mouse that inactivation of neurofibromin 1 (
Nf1
), a gene that is mutated in neurofibromatosis type 1, unlocks a latent oligodendrocyte lineage potential of neural stem cells to produce all three lineages
in vivo
.
End...
Alternative Titles
Full title
Latent tri-lineage potential of adult hippocampal neural stem cells revealed by Nf1 inactivation
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4661096
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4661096
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/nn.4159
