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The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell t...

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662931

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

About this item

Full title

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2015-12, Vol.17 (12), p.1523-1535

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

For nearly a century developmental biologists have recognized that cells from embryos can differ in their potential to differentiate into distinct cell types. Recently, it has been recognized that embryonic stem cells derived from both mice and humans exhibit two stable yet epigenetically distinct states of pluripotency: naive and primed. We now sh...

Alternative Titles

Full title

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662931

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4662931

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/ncb3264

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