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Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival

Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665787

Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival

About this item

Full title

Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival

Publisher

United States: American Society for Clinical Investigation

Journal title

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4655-4665

Language

English

Formats

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Rabbit-generated antithymocyte globulins (ATGs), which target human T cells, are widely used as immunosuppressive agents during treatment of kidney allograft recipients. However, ATGs can induce immune complex diseases, including serum sickness disease (SSD). Rabbit and human IgGs have various antigenic differences, including expression of the sial...

Alternative Titles

Full title

Rabbit antithymocyte globulin-induced serum sickness disease and human kidney graft survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665787

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4665787

Other Identifiers

ISSN

0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI82267

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