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Rapid reverse genetic screening using CRISPR in zebrafish

Rapid reverse genetic screening using CRISPR in zebrafish

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4667794

Rapid reverse genetic screening using CRISPR in zebrafish

About this item

Full title

Rapid reverse genetic screening using CRISPR in zebrafish

Publisher

New York: Nature Publishing Group US

Journal title

Nature methods, 2015-06, Vol.12 (6), p.535-540

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Targeting 48 loci in a pooled CRISPR-Cas9 screen reveals new genes essential for electrical-synapse formation.
Identifying genes involved in biological processes is critical for understanding the molecular building blocks of life. We used engineered CRISPR (clustered regularly interspaced short palindromic repeats) to efficiently mutate specific...

Alternative Titles

Full title

Rapid reverse genetic screening using CRISPR in zebrafish

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4667794

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4667794

Other Identifiers

ISSN

1548-7091

E-ISSN

1548-7105

DOI

10.1038/nmeth.3360

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